Search results for "Molybdenum pentachloride"

Mild, Fast, and Easy To Conduct MoCl5-Mediated Dehydrogenative Coupling Reactions in Flow

2018

A convenient and straightforward approach to performing oxidative coupling reactions in flow is presented. A collection of electron-rich benzene derivatives was subjected to this protocol, and the distinct utility of molybdenum pentachloride (MoCl5) is established. Using this unexplored protocol, biphenyls could be obtained in 21–91% isolated yield. This simple protocol opens a new chapter in reagent-mediated dehydrogenative coupling reactions, and yields are compared to classical approaches.

Molybdenum Pentachloride Mediated Synthesis of Spirocyclic Compounds by Intramolecular Oxidative Coupling

2015

The oxidative treatment of (m)ethyl 2-aryl cinnamates equipped with methoxy groups in position 4 of the phenyl moiety promote the formation of cyclohexadienone substructures. This dealkylative oxidative C–C coupling gives access to spirocyclic compounds and avoids the construction of the corresponding phenanthrenes. Furthermore, the transformation can be expanded to other spirocyclic systems.

Oxidative transformation of aryls using molybdenum pentachloride.

2012

Molybdenum pentachloride combines a strong Lewis acid character with an unusually high oxidation potential creating a powerful reagent for oxidative transformations. Since the oxidative coupling reaction of aryls is induced at an extraordinarily high reaction rate, a variety of labile groups, e.g. iodo, tert-alkyl, etc., are tolerated on the aromatic core. Furthermore, the co-formed molybdenum salts can either be exploited for template effects to obtain uncommon geometries in a preferred manner, or redox-play starts after aqueous workup. Therefore MoCl(5) represents a unique and easily available reagent.

ChemInform Abstract: Molybdenum Pentachloride Mediated Synthesis of Spirocyclic Compounds by Intramolecular Oxidative Coupling.

2016

Oxidative treatment of 4-methoxy substituted 2-aryl cinnamates leads to an dealkylative C—C coupling and gives access to spirocyclic compounds.

ChemInform Abstract: Molybdenum Pentachloride. A Multifaceted Reagent for Efficient Coupling of Aromatics

2015

Synthesis of highly functionalized 9,10-phenanthrenequinones by oxidative coupling using MoCl5.

2012

The strong oxidative power of molybdenum pentachloride gives rise to an efficient oxidative C-C bond formation of benzil derivatives to the corresponding 9,10-phenanthrenequinones. A highly complementary method to previous approaches was developed. The required derivatives are accessible in a modular fashion and in excellent yields. By this approach the orchid-derived natural product cypripediquinone A was synthesized for the first time.

ChemInform Abstract: Oxidative Transformation of Aryls Using Molybdenum Pentachloride

2012

Molybdenum pentachloride combines a strong Lewis acid character with an unusually high oxidation potential creating a powerful reagent for oxidative transformations. Since the oxidative coupling reaction of aryls is induced at an extraordinarily high reaction rate, a variety of labile groups, e.g. iodo, tert-alkyl, etc., are tolerated on the aromatic core. Furthermore, the co-formed molybdenum salts can either be exploited for template effects to obtain uncommon geometries in a preferred manner, or redox-play starts after aqueous workup. Therefore MoCl5 represents a unique and easily available reagent.

Modular Access to 9,9-Spirobifluorenes by Oxidative Coupling Using Molybdenum Pentachloride

2013

The strong oxidizing agent molybdenum pentachloride was used for an efficient direct C–C bond formation of 9,9-diarylfluorenes to the corresponding 9,9-spirobifluorenes. Thus, a versatile method that is compatible with labile groups, such as iodo moieties, was established. By this approach important building blocks for light emitting polymers were synthesized in high yields.

Versatile oxidative approach to carbazoles and related compounds using MoCl5.

2013

The unique oxidizing power of molybdenum pentachloride provides an easy to perform, versatile, and high yielding method to construct carbazoles and the corresponding dibenzo analogues of thiophene, furan, and selenophene. The coupling reaction tolerates a variety of functional groups. The synthesis is highly modular. By this approach a precursor for the naturally occurring carbazole koenigicine was prepared.

ChemInform Abstract: Modular Access to 9,9-Spirobifluorenes by Oxidative Coupling Using Molybdenum Pentachloride.

2013

The reactions of diarylfluorenes and substrates (III) or (V) result in formation of spirobifluorenes and fluorene derivatives.